The Argatroban and Tissue-Type Plasminogen Activator Stroke Study | Zendy

Andrew D. Barreto | Zendy; Andrei V. Alexandrov | Zendy; Pat Lyden | Zendy; Jessica Lee | Zendy; Sheryl MartinSchild | Zendy; Loren Shen | Zendy; TzuChing Wu | Zendy; April Sisson | Zendy; Renganayaki Pandurengan | Zendy; Zhongxue Chen | Zendy; Mohammad H. Rahbar | Zendy; Clotilde Balucani | Zendy; Kristian Barlinn | Zendy; Rebecca Sugg | Zendy; Zsolt Garami | Zendy; Georgios Tsivgoulis | Zendy; Nicole R. Gonzales | Zendy; Sean I. Savitz | Zendy; Robert Mikulík | Zendy; Andrew M. Demchuk | Zendy; James C. Grotta | Zendy

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The Argatroban and Tissue-Type Plasminogen Activator Stroke Study

Author(s) -

Andrew D. Barreto,

Andrei V. Alexandrov,

Pat Lyden,

Jessica Lee,

Sheryl MartinSchild,

Loren Shen,

TzuChing Wu,

April Sisson,

Renganayaki Pandurengan,

Zhongxue Chen,

Mohammad H. Rahbar,

Clotilde Balucani,

Kristian Barlinn,

Rebecca Sugg,

Zsolt Garami,

Georgios Tsivgoulis,

Nicole R. Gonzales,

Sean I. Savitz,

Robert Mikulík,

Andrew M. Demchuk,

James C. Grotta

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.625574

Subject(s) - argatroban , medicine , interquartile range , intracerebral hemorrhage , thrombolysis , stroke (engine) , bolus (digestion) , modified rankin scale , anesthesia , tissue plasminogen activator , partial thromboplastin time , direct thrombin inhibitor , transcranial doppler , surgery , atrial fibrillation , warfarin , ischemic stroke , ischemia , glasgow coma scale , coagulation , thrombin , dabigatran , platelet , mechanical engineering , engineering , myocardial infarction

Argatroban is a direct thrombin inhibitor that safely augments recanalization achieved by tissue-type plasminogen activator (tPA) in animal stroke models. The Argatroban tPA Stroke Study was an open-label, pilot safety study of tPA plus Argatroban in patients with ischemic stroke due to proximal intracranial occlusion.

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