Age and Outcomes After Carotid Stenting and Endarterectomy | Zendy

Jenifer H. Voeks | Zendy; George Howard | Zendy; Gary S. Roubin | Zendy; Mahmoud B. Malas | Zendy; David J. Cohen | Zendy; W. Charles Sternbergh | Zendy; Herbert D. Aronow | Zendy; Mark K. Eskandari | Zendy; Alice J. Sheffet | Zendy; Brajesh K. Lal | Zendy; James F. Meschia | Zendy; Thomas G. Brott | Zendy

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Age and Outcomes After Carotid Stenting and Endarterectomy

Author(s) -

Jenifer H. Voeks,

George Howard,

Gary S. Roubin,

Mahmoud B. Malas,

David J. Cohen,

W. Charles Sternbergh,

Herbert D. Aronow,

Mark K. Eskandari,

Alice J. Sheffet,

Brajesh K. Lal,

James F. Meschia,

Thomas G. Brott

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.624155

Subject(s) - medicine , carotid endarterectomy , clinical endpoint , stroke (engine) , stenosis , relative risk , confidence interval , endarterectomy , carotid stenting , surgery , cardiology , randomized controlled trial , mechanical engineering , engineering

High stroke event rates among carotid artery stenting (CAS)-treated patients in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) lead-in registry generated an a priori hypothesis that age may modify the relative efficacy of CAS versus carotid endarterectomy (CEA). In the primary CREST report, we previously noted significant effect modification by age. Here we extend this investigation by examining the relative efficacy of the components of the primary end point, the treatment-specific impact of age, and contributors to the increasing risk in CAS-treated patients at older ages.

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