Remote Ischemic Per-Conditioning | Zendy

Cecil D. Hahn | Zendy; Cedric Manlhiot | Zendy; Michael Rahbek Schmidt | Zendy; Torsten Toftegaard Nielsen | Zendy; Andrew N. Redington | Zendy

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Remote Ischemic Per-Conditioning

Author(s) -

Cecil D. Hahn,

Cedric Manlhiot,

Michael Rahbek Schmidt,

Torsten Toftegaard Nielsen,

Andrew N. Redington

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.622340

Subject(s) - medicine , ischemia , neuroprotection , ischemic preconditioning , anesthesia , conditioning , stroke (engine) , cardiology , mechanical engineering , statistics , mathematics , engineering

Remote ischemic preconditioning is a phenomenon by which a short period of sublethal ischemia to an organ protects against subsequent ischemia in another organ. We have recently demonstrated that remote ischemic conditioning by transient hind limb ischemia delivered during ischemia and before reperfusion can provide potent cardioprotection, a phenomenon we termed per-conditioning. This study evaluated whether remote ischemic per-conditioning may provide neuroprotection in a clinically relevant rat model of acute ischemic stroke.

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