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Low Carotid Calcium Score Is Associated With Higher Levels of Glycosaminoglycans, Tumor Necrosis Factor-Alpha, and Parathyroid Hormone in Human Carotid Plaques
Author(s) -
Andreas Edsfeldt,
Nuno Dias,
Barbara Elmståhl,
Felipe Martins Müller,
Katarina Berg,
Mihaela Nitulescu,
Ana Persson,
Olle Ekberg,
Isabel Gonçalves
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.620658
Subject(s) - medicine , glycosaminoglycan , calcium , tumor necrosis factor alpha , calcification , parathyroid hormone , endocrinology , proinflammatory cytokine , monocyte , inflammation , anatomy
Computed tomography (CT) is used to study coronary artery plaques, but little is known about its potential to characterize plaque composition. This study assesses the relation between carotid calcium score (CCS) by CT and plaque composition, namely extracellular matrix, inflammatory mediators, and calcium metabolites.

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