Siblings With Ischemic Stroke Study
Author(s) -
James F. Meschia,
Michael A. Nalls,
Mar Matarín,
Thomas G. Brott,
Robert D. Brown,
John Hardy,
Brett Kissela,
Stephen S. Rich,
Andrew Singleton,
Dena G. Hernandez,
Luigi Ferrucci,
Kerra Pearce,
M. Keller,
Bradford B. Worrall
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.620484
Subject(s) - medicine , stroke (engine) , sibling , single nucleotide polymorphism , proband , concordance , ischemic stroke , genome wide association study , genotype , genetics , ischemia , gene , mutation , biology , mechanical engineering , psychology , developmental psychology , engineering
Ischemic stroke has a strong familial component to risk. The Siblings With Ischemic Stroke Study (SWISS) is a genome-wide, family-based analysis that included use of imputed genotypes. The Siblings With Ischemic Stroke Study was conducted to examine the associations between single-nucleotide polymorphisms (SNPs) and risk of stroke and stroke subtypes within pairs.
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