Age, Antipsychotics, and the Risk of Ischemic Stroke in the Veterans Health Administration
Author(s) -
Shirley Wang,
Crystal D. Linkletter,
David D. Dore,
Vincent Mor,
Stephen L. Buka,
Malcolm Maclure
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.617191
Subject(s) - medicine , stroke (engine) , confounding , odds ratio , odds , antipsychotic , emergency medicine , pediatrics , psychiatry , schizophrenia (object oriented programming) , logistic regression , mechanical engineering , engineering
Time-dependent effects of antipsychotics on risk of stroke and potential effect modification by age have not been fully investigated. A case-case-time-control design uses within- and between-case comparisons to evaluate short-term effects at the same time as adjusting for unmeasured time-invariant confounders and exposure-time trends.
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