Open AccessIncreased Blood–Brain Barrier Permeability and Brain Edema After Focal Cerebral Ischemia Induced by Hyperlipidemia
Author(s) -
Ayman ElAli,
Thorsten R. Doeppner,
Anil Zechariah,
Dirk M. Hermann
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.615559
Subject(s) - medicine , occludin , extravasation , blood–brain barrier , hyperlipidemia , rhoa , cerebral edema , ischemia , endocrinology , pathology , tight junction , central nervous system , biochemistry , biology , signal transduction , diabetes mellitus
Hyperlipidemia is a highly prevalent risk factor for ischemic stroke. Its impact on brain injury and blood-brain barrier permeability, so far, has not been assessed in animal models of ischemic stroke.
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