Intracranial Hemorrhage, Outcome, and Mortality After Intra-Arterial Therapy for Acute Ischemic Stroke in Patients Under Oral Anticoagulants | Zendy

Gian Marco De Marchis | Zendy; Simon Jung | Zendy; Giuseppe Colucci | Zendy; Niklaus Meier | Zendy; Urs Fischer | Zendy; Anja Weck | Zendy; MarieLuise Mono | Zendy; Aekaterini Galimanis | Zendy; Heinrich P. Mattle | Zendy; Gerhard Schroth | Zendy; Jan Gralla | Zendy; Marcel Arnold | Zendy; Caspar Brekenfeld | Zendy

Open Access

Intracranial Hemorrhage, Outcome, and Mortality After Intra-Arterial Therapy for Acute Ischemic Stroke in Patients Under Oral Anticoagulants

Author(s) -

Gian Marco De Marchis,

Simon Jung,

Giuseppe Colucci,

Niklaus Meier,

Urs Fischer,

Anja Weck,

MarieLuise Mono,

Aekaterini Galimanis,

Heinrich P. Mattle,

Gerhard Schroth,

Jan Gralla,

Marcel Arnold,

Caspar Brekenfeld

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.615476

Subject(s) - medicine , modified rankin scale , interquartile range , stroke (engine) , intracerebral hemorrhage , tissue plasminogen activator , mortality rate , surgery , anesthesia , ischemic stroke , ischemia , subarachnoid hemorrhage , mechanical engineering , engineering

Use of intravenous tissue-type plasminogen activator (IV tPA) for acute ischemic stroke is restricted to patients with an international normalized ratio (INR) less than 1.7. However, a recent study showed increased risk of symptomatic intracranial hemorrhage after IV tPA use in patients with oral anticoagulants (OAC) even with an INR less than 1.7. The present study assessed the risk of symptomatic intracranial hemorrhage, clinical outcome, and mortality after intra-arterial therapy (IAT) in patients with and without previous use of OAC.

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