Low Plasma Arginine:Asymmetric Dimethyl Arginine Ratios Predict Mortality After Intracranial Aneurysm Rupture | Zendy

Jonatan Myrup Staalsø | Zendy; Anita Bergström | Zendy; Troels Edsen | Zendy; Pia Weikop | Zendy; Bertil Romner | Zendy; Niels Vidiendal Olsen | Zendy

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Low Plasma Arginine:Asymmetric Dimethyl Arginine Ratios Predict Mortality After Intracranial Aneurysm Rupture

Author(s) -

Jonatan Myrup Staalsø,

Anita Bergström,

Troels Edsen,

Pia Weikop,

Bertil Romner,

Niels Vidiendal Olsen

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.000605

Subject(s) - medicine , arginine , aneurysm , cardiology , surgery , amino acid , biochemistry , chemistry

Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthases, predicts mortality in cardiovascular disease and has been linked to cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH). In this prospective study, we assessed whether circulating ADMA, arginine:ADMA ratio, and nitrite/nitrate levels were associated with survival and cerebral vasospasm in SAH patients.

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