Low Dehydroepiandrosterone Sulfate is Associated With Increased Risk of Ischemic Stroke Among Women
Author(s) -
Monik C. Jiménez,
Qi Sun,
Markus Schürks,
Stephanie E. Chiuve,
Frank B. Hu,
JoAnn E. Manson,
Kathryn M. Rexrode
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.000485
Subject(s) - medicine , dehydroepiandrosterone sulfate , stroke (engine) , ischemic stroke , dehydroepiandrosterone , cardiology , ischemia , hormone , androgen , mechanical engineering , engineering
Previous research suggests greater risk of coronary heart disease with lower levels of the adrenal steroid dehydroepiandrosterone sulfate (DHEAS). No studies have examined the association between DHEAS and risk of ischemic stroke. DHEAS may influence ischemic stroke risk through atherosclerotic-related mechanisms (endothelial function and smooth muscle cell proliferation) or insulin resistance.
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