Minimally Invasive Surgery Plus Recombinant Tissue-type Plasminogen Activator for Intracerebral Hemorrhage Evacuation Decreases Perihematomal Edema | Zendy

W. Andrew Mould | Zendy; J. Ricardo Carhuapoma | Zendy; John Muschelli | Zendy; Karen Lane | Zendy; Timothy C. Morgan | Zendy; Nichol McBee | Zendy; Amanda J. Bistran-Hall | Zendy; Natalie Ullman | Zendy; Paul Vespa | Zendy; Neil A. Martin | Zendy; Issam A. Awad | Zendy; Mario Zuccarello | Zendy; Daniel F. Hanley | Zendy

Open Access

Minimally Invasive Surgery Plus Recombinant Tissue-type Plasminogen Activator for Intracerebral Hemorrhage Evacuation Decreases Perihematomal Edema

Author(s) -

W. Andrew Mould,

J. Ricardo Carhuapoma,

John Muschelli,

Karen Lane,

Timothy C. Morgan,

Nichol McBee,

Amanda J. Bistran-Hall,

Natalie Ullman,

Paul Vespa,

Neil A. Martin,

Issam A. Awad,

Mario Zuccarello,

Daniel F. Hanley

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.000411

Subject(s) - medicine , intracerebral hemorrhage , plasminogen activator , surgery , edema , tissue plasminogen activator , recombinant tissue plasminogen activator , stroke (engine) , t plasminogen activator , recombinant dna , vascular disease , ischemic stroke , subarachnoid hemorrhage , ischemia , mechanical engineering , biochemistry , chemistry , modified rankin scale , engineering , gene

Perihematomal edema (PHE) can worsen outcomes after intracerebral hemorrhage (ICH). Reports suggest that blood degradation products lead to PHE. We hypothesized that hematoma evacuation will reduce PHE volume and that treatment with recombinant tissue-type plasminogen activator (rt-PA) will not exacerbate it.

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