Effect of Dose and Combination of Antihypertensives on Interindividual Blood Pressure Variability
Author(s) -
Alastair J.S. Webb,
Peter M. Rothwell
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.611566
Subject(s) - medicine , blood pressure , randomization , randomized controlled trial , calcium channel blocker , stroke (engine) , clinical trial , antihypertensive drug , cardiology , mechanical engineering , engineering
Recent studies have shown that visit-to-visit blood pressure variability is a powerful risk factor for stroke, is reduced by calcium channel blockers and diuretics, and increased by β-blockers. However, it is unknown whether these effects are dose-dependent and persist in combination with other drugs.
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