Open AccessLow Body Temperature Does Not Compromise the Treatment Effect of Alteplase
Author(s) -
Jennifer S. Lees,
Nishant K. Mishra,
Monica Saini,
Patrick D. Lyden,
Ashfaq Shuaib
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.611210
Subject(s) - medicine , modified rankin scale , stroke (engine) , hypothermia , ischemic stroke , physical therapy , ischemia , mechanical engineering , engineering
Hypothermia is neuroprotective in ischemic stroke models. The influence of baseline body temperature on outcomes after thrombolytic therapy is unclear. We examined outcomes after alteplase treatment across baseline body temperature for patients with ischemic stroke in data held within the Virtual International Stroke Trials Archive (VISTA; 1998 to 2007).
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