White Matter Hyperintensity Penumbra | Zendy

Pauline Maillard | Zendy; Evan Fletcher | Zendy; Danielle Harvey | Zendy; Owen Carmichael | Zendy; Bruce Reed | Zendy; Dan Mungas | Zendy; Charles DeCarli | Zendy

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White Matter Hyperintensity Penumbra

Author(s) -

Pauline Maillard,

Evan Fletcher,

Danielle Harvey,

Owen Carmichael,

Bruce Reed,

Dan Mungas,

Charles DeCarli

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.609768

Subject(s) - white matter , fractional anisotropy , diffusion mri , hyperintensity , medicine , leukoaraiosis , magnetic resonance imaging , cardiology , radiology

White matter hyperintensities (WMHs) are associated with progressive age-related cognitive decline and cardiovascular risk factors, but their biological relevance as indicators of generalized white matter injury is unclear. Diffusion tensor imaging provides more sensitive indications of subtle white matter disruption and can therefore clarify whether WMHs represent foci of generalized white matter damage that extends over a broader neighborhood.

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