Stress Worsens Endothelial Function and Ischemic Stroke via Glucocorticoids | Zendy

Mustafa Balkaya | Zendy; Vincent Prinz | Zendy; Florian Custodis | Zendy; Karen Gertz | Zendy; Golo Kronenberg | Zendy; Jan Kroeber | Zendy; Klaus Fink | Zendy; Ralph Plehm | Zendy; Peter Gass | Zendy; Ulrich Laufs | Zendy; Matthias Endres | Zendy

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Stress Worsens Endothelial Function and Ischemic Stroke via Glucocorticoids

Author(s) -

Mustafa Balkaya,

Vincent Prinz,

Florian Custodis,

Karen Gertz,

Golo Kronenberg,

Jan Kroeber,

Klaus Fink,

Ralph Plehm,

Peter Gass,

Ulrich Laufs,

Matthias Endres

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.607705

Subject(s) - medicine , chronic stress , mifepristone , endothelial dysfunction , endothelium , stroke (engine) , antiglucocorticoid , endocrinology , nitric oxide , nitric oxide synthase , glucocorticoid receptor , ischemia , middle cerebral artery , lesion , anesthesia , glucocorticoid , surgery , biology , pregnancy , mechanical engineering , genetics , engineering

Chronic stress is associated with increased stroke risk. However, the underlying pathophysiological mechanisms are poorly understood. We examined the effects of chronic stress on endothelial function and ischemic brain injury in a mouse model.

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