Atherosclerotic Plaque Vulnerability as an Explanation for the Increased Risk of Stroke in Elderly Undergoing Carotid Artery Stenting | Zendy

Guus W. van Lammeren | Zendy; B.L. Reichmann | Zendy; Frans L. Moll | Zendy; Michiel L. Bots | Zendy; Dominique P.V. de Kleijn | Zendy; JeanPaul P.M. de Vries | Zendy; Gerard Pasterkamp | Zendy; Gert J. de Borst | Zendy

Open Access

Atherosclerotic Plaque Vulnerability as an Explanation for the Increased Risk of Stroke in Elderly Undergoing Carotid Artery Stenting

Author(s) -

Guus W. van Lammeren,

B.L. Reichmann,

Frans L. Moll,

Michiel L. Bots,

Dominique P.V. de Kleijn,

JeanPaul P.M. de Vries,

Gerard Pasterkamp,

Gert J. de Borst

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.607382

Subject(s) - medicine , stroke (engine) , cardiology , carotid arteries , vulnerability (computing) , carotid stenting , carotid endarterectomy , mechanical engineering , engineering , computer security , computer science

Recent randomized trials showed an increased periprocedural risk for stroke with increasing age in patients undergoing carotid artery stenting. Manipulation of atherosclerotic plaques during carotid artery stenting can result in plaque rupture with subsequent superimposed thrombus formation, embolization, and cerebrovascular events. We hypothesized that atherosclerotic plaques become more unstable with increasing age and thereby might provide insight into the age-related increased risk of cerebrovascular events during carotid artery stenting.

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