Association of Early National Institutes of Health Stroke Scale Improvement With Vessel Recanalization and Functional Outcome After Intravenous Thrombolysis in Ischemic Stroke | Zendy

T. V. Kharitonova | Zendy; Robert Mikulík | Zendy; Risto O. Roine | Zendy; Lauri Soinne | Zendy; Niaz Ahmed | Zendy; Nils Wahlgren | Zendy

Open Access

Association of Early National Institutes of Health Stroke Scale Improvement With Vessel Recanalization and Functional Outcome After Intravenous Thrombolysis in Ischemic Stroke

Author(s) -

T. V. Kharitonova,

Robert Mikulík,

Risto O. Roine,

Lauri Soinne,

Niaz Ahmed,

Nils Wahlgren

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.606194

Subject(s) - medicine , thrombolysis , modified rankin scale , receiver operating characteristic , stroke (engine) , logistic regression , angiography , cohort , occlusion , cardiology , ischemic stroke , ischemia , mechanical engineering , myocardial infarction , engineering

Early neurological improvement (ENI) after thrombolytic therapy of acute stroke has been linked with recanalization and favorable outcome, although its definition shows considerable variation. We tested the ability of ENI, as defined in previous publications, to predict vessel recanalization and 3-month functional outcome after intravenous thrombolysis recorded in an extensive patient cohort in the Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR).

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