Human Umbilical Mesenchymal Stem Cells Promote Recovery After Ischemic Stroke | Zendy

YuChing Lin | Zendy; Tsui-Ling Ko | Zendy; YangHsin Shih | Zendy; Maan-Yuh Anya Lin | Zendy; Tz-Win Fu | Zendy; Hsiao-Sheng Hsiao | Zendy; Jung-Yu C. Hsu | Zendy; Yu-Show Fu | Zendy

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Human Umbilical Mesenchymal Stem Cells Promote Recovery After Ischemic Stroke

Author(s) -

YuChing Lin,

Tsui-Ling Ko,

YangHsin Shih,

Maan-Yuh Anya Lin,

Tz-Win Fu,

Hsiao-Sheng Hsiao,

Jung-Yu C. Hsu,

Yu-Show Fu

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.603621

Subject(s) - medicine , transplantation , neuroprotection , mesenchymal stem cell , neurotrophic factors , stroke (engine) , basic fibroblast growth factor , cortex (anatomy) , ischemia , stem cell , surgery , anesthesia , pathology , growth factor , neuroscience , receptor , microbiology and biotechnology , biology , mechanical engineering , engineering

Stroke is a cerebrovascular defect that leads to many adverse neurological complications. Current pharmacological treatments for stroke remain unclear in their effectiveness, whereas stem cell transplantation shows considerable promise. Previously, we have shown that human umbilical mesenchymal stem cells (HUMSCs) can differentiate into neurons in neuronal-conditioned medium. Here we evaluate the therapeutic potential of HUMSC transplantation for ischemic stroke in rats.

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