Isoflurane Enhanced Hemorrhagic Transformation by Impairing Antioxidant Enzymes in Hyperglycemic Rats With Middle Cerebral Artery Occlusion | Zendy

Qin Hu | Zendy; Qingyi Ma | Zendy; Yan Zhan | Zendy; HE Zhaohui | Zendy; Jiping Tang | Zendy; Changman Zhou | Zendy; John H. Zhang | Zendy

Open Access

Isoflurane Enhanced Hemorrhagic Transformation by Impairing Antioxidant Enzymes in Hyperglycemic Rats With Middle Cerebral Artery Occlusion

Author(s) -

Qin Hu,

Qingyi Ma,

Yan Zhan,

HE Zhaohui,

Jiping Tang,

Changman Zhou,

John H. Zhang

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.603142

Subject(s) - medicine , isoflurane , malondialdehyde , anesthesia , neuroprotection , ischemia , superoxide dismutase , middle cerebral artery , oxidative stress , nitrotyrosine , pharmacology , nitric oxide , nitric oxide synthase

Because the potential neuroprotective effect of isoflurane is controversial, we attempted to study whether isoflurane after treatment provides neuroprotection in a rat model of hyperglycemia-induced ischemic hemorrhagic transformation.

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