Stem Cell Research in Stroke | Zendy

Olle Lindvall | Zendy; Zaal Kokaia | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Stem Cell Research in Stroke

Author(s) -

Olle Lindvall,

Zaal Kokaia

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.599654

Subject(s) - medicine , remyelination , stroke (engine) , stem cell , neuroprotection , stem cell therapy , neuroscience , transplantation , neural stem cell , stroke recovery , regeneration (biology) , angiogenesis , pharmacology , surgery , central nervous system , physical therapy , microbiology and biotechnology , biology , mechanical engineering , myelin , rehabilitation , engineering

Stem cell-based approaches hold much promise as potential novel treatments to restore function after stroke. Studies in animal models have shown that stem cell transplantation can improve function by replacing neurons or by trophic actions, modulation of inflammation, promotion of angiogenesis, remyelination and axonal plasticity, and neuroprotection. Endogenous neural stem cells are also potential therapeutic targets because they produce new neurons after stroke. Clinical trials are ongoing but there is currently no proven stem cell-based therapy for stroke. Preclinical studies and clinical research will be needed to optimize the therapeutic benefit and minimize the risks of stem cells in stroke.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research