Effects of Neural Progenitor Cells on Sensorimotor Recovery and Endogenous Repair Mechanisms After Photothrombotic Stroke
Author(s) -
Jens Minnerup,
Jeong Beom Kim,
Antje Schmidt,
Kai Diederich,
Henrike Bauer,
Matthias Schilling,
JanKolja Strecker,
E. Bernd Ringelstein,
Claudia Sommer,
Hans R. Schöler,
WolfRüdiger Schäbitz
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.599282
Subject(s) - neurogenesis , medicine , endogeny , transplantation , neural stem cell , progenitor cell , neuroplasticity , neuroscience , stroke (engine) , ischemia , stroke recovery , stem cell , biology , microbiology and biotechnology , rehabilitation , mechanical engineering , physical therapy , psychiatry , engineering
Intravenous neural progenitor cell (NPC) treatment was shown to improve functional recovery after experimental stroke. The underlying mechanisms, however, are not completely understood so far. Here, we investigated the effects of systemic NPC transplantation on endogenous neurogenesis and dendritic plasticity of host neurons.
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