Open AccessSulfonylurea Use Before Stroke Does Not Influence Outcome
Author(s) -
Christopher G. Favilla,
Michael T. Mullen,
Myzoon Ali,
Peter Higgins,
Scott E. Kasner
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.599274
Subject(s) - medicine , modified rankin scale , stroke (engine) , sulfonylurea , diabetes mellitus , cohort , physical therapy , ischemic stroke , ischemia , endocrinology , mechanical engineering , engineering
Sulfonylureas block nonselective cation channels and lower serum glucose and are neuroprotective in animal models of ischemic stroke. Human data on sulfonylureas in acute stroke are sparse and conflicting. We aimed to measure the potential neuroprotective effect of prestroke sulfonylurea use in diabetic patients.
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