Subtherapeutic Warfarin Is Not Associated With Increased Hemorrhage Rates in Ischemic Strokes Treated With Tissue Plasminogen Activator | Zendy

Mervyn D.I. Vergouwen | Zendy; Leanne K. Casaubon | Zendy; Richard H. Swartz | Zendy; Jiming Fang | Zendy; Melissa Stamplecoski | Zendy; Moira K. Kapral | Zendy; Frank L. Silver | Zendy

Open Access

Subtherapeutic Warfarin Is Not Associated With Increased Hemorrhage Rates in Ischemic Strokes Treated With Tissue Plasminogen Activator

Author(s) -

Mervyn D.I. Vergouwen,

Leanne K. Casaubon,

Richard H. Swartz,

Jiming Fang,

Melissa Stamplecoski,

Moira K. Kapral,

Frank L. Silver

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.599183

Subject(s) - medicine , warfarin , intracerebral hemorrhage , tissue plasminogen activator , stroke (engine) , cohort , odds ratio , surgery , anesthesia , atrial fibrillation , subarachnoid hemorrhage , mechanical engineering , engineering

Concern exists that preadmission warfarin use may be associated with an increased risk of intracerebral hemorrhage in patients with ischemic stroke receiving intravenous tissue plasminogen activator, even in those with an international normalized ratio <1.7. However, evidence to date has been derived from a small single-center cohort of patients.

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