A Unique MicroRNA Signature Associated With Plaque Instability in Humans | Zendy

Francesco Cipollone | Zendy; Lara Felicioni | Zendy; Riccardo Sarzani | Zendy; S Ucchino | Zendy; Francesco Spigonardo | Zendy; Claudia Mandolini | Zendy; Sara Malatesta | Zendy; Marco Bucci | Zendy; C. Mammarella | Zendy; Donato Santovito | Zendy; Federica de Lutiis | Zendy; Antonio Marchetti | Zendy; Andrea Mezzetti | Zendy; Fiamma Buttitta | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A Unique MicroRNA Signature Associated With Plaque Instability in Humans

Author(s) -

Francesco Cipollone,

Lara Felicioni,

Riccardo Sarzani,

S Ucchino,

Francesco Spigonardo,

Claudia Mandolini,

Sara Malatesta,

Marco Bucci,

C. Mammarella,

Donato Santovito,

Federica de Lutiis,

Antonio Marchetti,

Andrea Mezzetti,

Fiamma Buttitta

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.597575

Subject(s) - medicine , microrna , stroke (engine) , asymptomatic , pathology , bioinformatics , gene , biology , genetics , mechanical engineering , engineering

Atherosclerotic plaque rupture is considered the most important mechanism that underlies the onset of stroke, myocardial infarction, and sudden death. Several evidences demonstrated the pivotal role of inflammatory processes in plaque destabilization. MicroRNAs (miRNAs) are small endogenous RNAs and represent a new important class of gene regulators. Nevertheless, no data exist about the expression profile of miRNAs in atherosclerotic plaques. Thus, the aim of this study was to investigate the expression level of miRNAs in human plaques and to correlate it with clinical features of plaque destabilization.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research