Neuroprotection and Recovery

In this work, we review recent data on the actions of citicoline, citicoline is a drug with demonstrated neuroprotective properties in both animals and humans. Summary of Review- For neuroprotection, mechanisms involved are the improvement of cellular functions aimed to control excitotoxicity and to maintain cellular adenosine 5'-triphosphate levels by preserving membrane function and integrity at different levels. Importantly, these actions are theoretically achieved without interfering with possible underlying mechanisms for neurorepair. Furthermore, citicoline stimulates neuronal plasticity and improves sensorimotor recovery in the chronic phase of experimental stroke.