Diffusion Tensor MRI Reveals Chronic Alterations in White Matter Despite the Absence of a Visible Ischemic Lesion on Conventional MRI | Zendy

Ebeline Bihel | Zendy; Simon Roussel | Zendy; Jérôme Toutain | Zendy; Myriam Bernaudin | Zendy; Omar Touzani | Zendy

Open Access

Diffusion Tensor MRI Reveals Chronic Alterations in White Matter Despite the Absence of a Visible Ischemic Lesion on Conventional MRI

Author(s) -

Ebeline Bihel,

Simon Roussel,

Jérôme Toutain,

Myriam Bernaudin,

Omar Touzani

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.596650

Subject(s) - white matter , diffusion mri , medicine , fractional anisotropy , lesion , marmoset , ischemia , stroke (engine) , magnetic resonance imaging , pathology , neuroscience , radiology , cardiology , psychology , physics , thermodynamics , paleontology , biology

The impact of stroke on white matter is poorly described in preclinical investigations mainly based on rodents with a low white (WM)/gray matter ratio. Using diffusion tensor imaging, we evaluated WM alterations and correlated them with sensorimotor deficits after stroke in the marmoset, a nonhuman primate that displays a WM/gray matter ratio close to that of humans.

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