Open AccessThe Safety of Proton Pump Inhibitors and Clopidogrel in Patients After Stroke
Author(s) -
David N. Juurlink,
Tara Gomes,
Muhammad Mamdani,
David J. Gladstone,
Moira K. Kapral
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.596643
Subject(s) - medicine , clopidogrel , stroke (engine) , odds ratio , cohort , cohort study , cardiology , surgery , aspirin , mechanical engineering , engineering
evidence suggests that some proton pump inhibitors can attenuate the antiplatelet effect of clopidogrel. The significance of this potential drug interaction in patients with cerebrovascular disease is unknown.
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