The Spot Sign Is More Common in the Absence of Multiple Prior Microbleeds
Author(s) -
Andrea Evans,
Andrew M. Demchuk,
Sean Symons,
Dar Dowlatshahi,
David J. Gladstone,
Liying Zhang,
Allan J. Fox,
Richard I. Aviv
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.593970
Subject(s) - medicine , sign (mathematics) , stroke (engine) , pathology , mechanical engineering , engineering , mathematical analysis , mathematics
Mural thickening and permeability changes in patients with amyloid angiopathy (CAA) and chronic hypertension are implicated in the pathophysiology of multiple, chronic subclinical microbleeds. The Spot sign, contrast extravasation on CT angiography, predicts hematoma expansion and is presumed to represent acute vessel damage. We hypothesize that the Spot sign is more common in patients without multiple prior chronic microbleeds.
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