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Comparative Effectiveness of Hemostatic Therapy in Experimental Warfarin-Associated Intracerebral Hemorrhage
Author(s) -
Sergio Illanes,
Wei Zhou,
Sönke Schwarting,
Sabine Heiland,
Roland Veltkamp
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.593541
Subject(s) - medicine , intracerebral hemorrhage , warfarin , fresh frozen plasma , tranexamic acid , saline , prothrombin complex concentrate , anesthesia , hematoma , prothrombin time , hemostasis , coagulation , gastroenterology , surgery , platelet , blood loss , atrial fibrillation , subarachnoid hemorrhage
intracerebral hemorrhage associated with oral anticoagulants has a poor prognosis. Current treatment guidelines are based on case series and plausibility only, and a common consensus on effective hemostatic therapy is missing. We compared the effectiveness of diverse hemostatic approaches in a mouse model of warfarin-associated intracerebral hemorrhage.

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