Delayed Administration of Human Umbilical Tissue-Derived Cells Improved Neurological Functional Recovery in a Rodent Model of Focal Ischemia | Zendy

Li Zhang | Zendy; Yi Li | Zendy; Chunling Zhang | Zendy; Michael Chopp | Zendy; Anna Gosiewska | Zendy; Klaudyne Hong | Zendy

Open Access

Delayed Administration of Human Umbilical Tissue-Derived Cells Improved Neurological Functional Recovery in a Rodent Model of Focal Ischemia

Author(s) -

Li Zhang,

Yi Li,

Chunling Zhang,

Michael Chopp,

Anna Gosiewska,

Klaudyne Hong

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.593129

Subject(s) - medicine , neuroprotection , neurogenesis , stroke (engine) , saline , synaptogenesis , mesenchymal stem cell , ischemia , anesthesia , pathology , surgery , neuroscience , mechanical engineering , engineering , biology

The short time window required by neuroprotective strategies for successful treatment of patients with ischemic stroke precludes treatment for most. However, clinical therapies based on neuroregeneration might extend this therapeutic time window and thus address a significant unmet need. Human umbilical tissue-derived cells have shown great potential as neuroregenerative candidates for stroke treatment.

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