J-Shaped Association Between Serum Glucose and Functional Outcome in Acute Ischemic Stroke | Zendy

George Ntaios | Zendy; Marc Egli | Zendy; Mohamed Faouzi | Zendy; Patrik Michel | Zendy

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J-Shaped Association Between Serum Glucose and Functional Outcome in Acute Ischemic Stroke

Author(s) -

George Ntaios,

Marc Egli,

Mohamed Faouzi,

Patrik Michel

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.592170

Subject(s) - medicine , modified rankin scale , logistic regression , receiver operating characteristic , stroke (engine) , diabetes mellitus , area under the curve , multivariate analysis , ischemic stroke , univariate analysis , cardiology , endocrinology , ischemia , mechanical engineering , engineering

Hyperglycemia after stroke is associated with larger infarct volume and poorer functional outcome. In an animal stroke model, the association between serum glucose and infarct volume is described by a U-shaped curve with a nadir ≈7 mmol/L. However, a similar curve in human studies was never reported. The objective of the present study is to investigate the association between serum glucose levels and functional outcome in patients with acute ischemic stroke.

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