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The Stability of the Blood Oxygenation Level-Dependent Functional MRI Response to Motor Tasks Is Altered in Patients With Chronic Ischemic Stroke
Author(s) -
Kelley C. MazzettoBetti,
Renata Ferranti Leoni,
Octávio Marques PontesNeto,
Antônio Carlos dos Santos,
João Pereira Leite,
Afonso C. Silva,
Dráulio Barros de Araújo
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.590471
Subject(s) - medicine , stroke (engine) , general linear model , physical medicine and rehabilitation , statistical parametric mapping , functional magnetic resonance imaging , linear model , motor system , supplementary motor area , stroke recovery , primary motor cortex , magnetic resonance imaging , neuroscience , motor cortex , physical therapy , rehabilitation , psychology , radiology , computer science , machine learning , mechanical engineering , psychiatry , engineering , stimulation
Functional MRI is a powerful tool to investigate recovery of brain function in patients with stroke. An inherent assumption in functional MRI data analysis is that the blood oxygenation level-dependent (BOLD) signal is stable over the course of the examination. In this study, we evaluated the validity of such assumption in patients with chronic stroke.

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