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Efficacy of Intra-Arterial Fibrinolysis for Acute Ischemic Stroke: Incongruent Recanalization and Good Outcome Rates
Author(s) -
Hebah Hefzy,
Panayiotis Mitsias
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.590208
Subject(s) - medicine , fibrinolysis , modified rankin scale , thrombolysis , stroke (engine) , neurology , randomized controlled trial , cardiology , ischemic stroke , anesthesia , ischemia , myocardial infarction , mechanical engineering , engineering , psychiatry
To the Editor:Lee et al provided a useful meta-analysis of the efficacy of intra-arterial fibrinolysis as reported in randomized controlled trials.1 Several interesting observations were made regarding the effect of intra-arterial fibrinolysis on radiological and clinical end points. They show that despite a 46.8% partial or complete recanalization rate, the increase in the rate of good outcomes was only 14.8% and excellent outcomes only 13%. This was attributed to the …

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