Delayed Anti-Nogo-A Therapy Improves Function After Chronic Stroke in Adult Rats | Zendy

ShihYen Tsai | Zendy; Catherine M. Papadopoulos | Zendy; Martin E. Schwab | Zendy; Gwendolyn L. Kartje | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Delayed Anti-Nogo-A Therapy Improves Function After Chronic Stroke in Adult Rats

Author(s) -

ShihYen Tsai,

Catherine M. Papadopoulos,

Martin E. Schwab,

Gwendolyn L. Kartje

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.590083

Subject(s) - forelimb , medicine , stroke (engine) , neuroplasticity , immunotherapy , anesthesia , neuroscience , pathology , cancer , anatomy , biology , mechanical engineering , psychiatry , engineering

we have shown that anti-Nogo-A immunotherapy to neutralize the neurite growth inhibitory protein Nogo-A results in functional improvement and enhanced plasticity after ischemic stroke in the adult rat. The present study investigated whether functional improvement and neuronal plasticity can be induced by this immunotherapy when administered to the chronic stroke-impaired rat.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research