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Thrombolysis With 0.6 mg/kg Intravenous Alteplase for Acute Ischemic Stroke in Routine Clinical Practice
Author(s) -
Jyoji Nakagawara,
Kazuo Minematsu,
Yasushi Okada,
Norio Tanahashi,
Shinji Nagahiro,
Etsuro Mori,
Yukito Shinohara,
Takenori Yamaguchi
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.589606
Subject(s) - medicine , thrombolysis , modified rankin scale , confidence interval , stroke (engine) , observational study , subgroup analysis , christian ministry , surgery , ischemic stroke , myocardial infarction , ischemia , mechanical engineering , philosophy , theology , engineering
In Japan, alteplase at 0.6 mg/kg was approved in October 2005 for use within 3 hours of stroke onset by the Ministry of Health, Labor and Welfare (MHLW). The aim of the Japan post-Marketing Alteplase Registration Study (J-MARS), which was requested by MHLW at the time of approval, was to assess the safety and efficacy of 0.6 mg/kg alteplase in routine clinical practice for the Japanese.

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