Open AccessNiacin Treatment of Stroke Increases Synaptic Plasticity and Axon Growth in Rats
Author(s) -
Xu Cui,
Michael Chopp,
Alex Zacharek,
Cynthia J. Roberts,
Benjamin Buller,
Madalina Ion,
Jieli Chen
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.589333
Subject(s) - medicine , stroke (engine) , axon , niacin , neuroplasticity , neuroscience , synaptic plasticity , anatomy , psychiatry , receptor , biology , mechanical engineering , engineering
Niacin is the most effective medication in current clinical use for increasing high-density lipoprotein cholesterol. We tested the hypothesis that niacin treatment of stroke promotes synaptic plasticity and axon growth in the ischemic brain.
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