Definition of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies | Zendy

Mervyn D.I. Vergouwen | Zendy; Marinus Vermeulen | Zendy; J. van Gijn | Zendy; Gabriël J.E. Rinkel | Zendy; Eelco F. M. Wijdicks | Zendy; J. Paul Muizelaar | Zendy; A. D. Mendelow | Zendy; Seppo Juvela | Zendy; Howard Yonas | Zendy; Karel G. terBrugge | Zendy; R. Loch Macdonald | Zendy; Michael N. Diringer | Zendy; Joseph P. Broderick | Zendy; Jens P. Dreier | Zendy; Yvo B.W.E.M. Roos | Zendy

Open Access

Definition of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies

Author(s) -

Mervyn D.I. Vergouwen,

Marinus Vermeulen,

J. van Gijn,

Gabriël J.E. Rinkel,

Eelco F. M. Wijdicks,

J. Paul Muizelaar,

A. D. Mendelow,

Seppo Juvela,

Howard Yonas,

Karel G. terBrugge,

R. Loch Macdonald,

Michael N. Diringer,

Joseph P. Broderick,

Jens P. Dreier,

Yvo B.W.E.M. Roos

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.589275

Subject(s) - medicine , subarachnoid hemorrhage , observational study , ischemia , clinical trial , stroke (engine) , cardiology , surgery , mechanical engineering , engineering

In clinical trials and observational studies there is considerable inconsistency in the use of definitions to describe delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage. A major cause for this inconsistency is the combining of radiographic evidence of vasospasm with clinical features of cerebral ischemia, although multiple factors may contribute to DCI. The second issue is the variability and overlap of terms used to describe each phenomenon. This makes comparisons among studies difficult.

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