Isolation of Locally Derived Stem/Progenitor Cells From the Peri-Infarct Area That Do Not Migrate From the Lateral Ventricle After Cortical Stroke | Zendy

Issei S. Shimada | Zendy; Brittni M. Peterson | Zendy; Jeffrey L. Spees | Zendy

Open Access

Isolation of Locally Derived Stem/Progenitor Cells From the Peri-Infarct Area That Do Not Migrate From the Lateral Ventricle After Cortical Stroke

Author(s) -

Issei S. Shimada,

Brittni M. Peterson,

Jeffrey L. Spees

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.589010

Subject(s) - subventricular zone , neurogenesis , neural stem cell , progenitor cell , neuroblast , medicine , stem cell , cerebral cortex , middle cerebral artery , rostral migratory stream , anatomy , nestin , neuroscience , pathology , biology , microbiology and biotechnology , ischemia

Neurogenesis can arise from neural stem/progenitor cells of the subventricular zone after strokes involving both the cortex and striatum. However, it is controversial whether all types of stroke and strokes of different sizes activate neurogenesis from the subventricular zone niche. In contrast with cortical/striatal strokes, repair and remodeling after mild cortical strokes may involve to a greater extent local cortical stem/progenitor cells and cells from nonneurogenic niches.

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