Mechanisms of Osteopontin-Induced Stabilization of Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Rats | Zendy

Hidenori Suzuki | Zendy; Yu Hasegawa | Zendy; Kenji Kanamaru | Zendy; John H. Zhang | Zendy

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Mechanisms of Osteopontin-Induced Stabilization of Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Rats

Author(s) -

Hidenori Suzuki,

Yu Hasegawa,

Kenji Kanamaru,

John H. Zhang

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.586537

Subject(s) - osteopontin , mapk/erk pathway , small interfering rna , medicine , recombinant dna , subarachnoid hemorrhage , blood–brain barrier , pharmacology , phosphorylation , microbiology and biotechnology , transfection , chemistry , biology , biochemistry , central nervous system , gene

Osteopontin (OPN) is an inducible, multifunctional, extracellular matrix protein that may be protective against blood-brain barrier (BBB) disruption after subarachnoid hemorrhage (SAH). However, the protective mechanisms remain unclear.

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