Minor Allele C of Chromosome 1p32 Single Nucleotide Polymorphism rs11206510 Confers Risk of Ischemic Stroke in the Chinese Han Population | Zendy

Chengqi Xu | Zendy; Fan Wang | Zendy; Binbin Wang | Zendy; Xiuchun Li | Zendy; Cong Li | Zendy; Dan Wang | Zendy; Xin Xiong | Zendy; Pengyun Wang | Zendy; Qiulun Lu | Zendy; Xiaojing Wang | Zendy; Qin Yang | Zendy; Dan Yin | Zendy; Yufeng Huang | Zendy; Liying Ji | Zendy; Nan Wang | Zendy; Shanshan Chen | Zendy; Xiang Cheng | Zendy; Yuhua Liao | Zendy; Xu Ma | Zendy; DingFeng Su | Zendy; Guohua Chen | Zendy; Hao Xia | Zendy; Lisong Shi | Zendy; Xin Tu | Zendy; Qing K. Wang | Zendy

Open Access

Minor Allele C of Chromosome 1p32 Single Nucleotide Polymorphism rs11206510 Confers Risk of Ischemic Stroke in the Chinese Han Population

Author(s) -

Chengqi Xu,

Fan Wang,

Binbin Wang,

Xiuchun Li,

Cong Li,

Dan Wang,

Xin Xiong,

Pengyun Wang,

Qiulun Lu,

Xiaojing Wang,

Qin Yang,

Dan Yin,

Yufeng Huang,

Liying Ji,

Nan Wang,

Shanshan Chen,

Xiang Cheng,

Yuhua Liao,

Xu Ma,

DingFeng Su,

Guohua Chen,

Hao Xia,

Lisong Shi,

Xin Tu,

Qing K. Wang

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.583096

Subject(s) - medicine , odds ratio , cohort , single nucleotide polymorphism , minor allele frequency , population , allele , stroke (engine) , lipoprotein(a) , coronary artery disease , genotype , genetics , gastroenterology , cholesterol , lipoprotein , biology , gene , mechanical engineering , environmental health , engineering

Genome-wide association studies found that the common allele T of single nucleotide polymorphism rs11206510 on chromosome 1p32 was associated with increased low-density lipoprotein-cholesterol levels (LDL-C) and with risk of coronary artery disease (CAD) in white populations. The goals of this study are to determine whether rs11206510 is associated with LDL-C and CAD in a different ethnic population, namely a Chinese cohort, and to investigate whether rs11206510 is associated with ischemic stroke.

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