Coated Platelet Levels Correlate With Bleed Volume in Patients With Spontaneous Intracerebral Hemorrhage
Author(s) -
Călin I. Prodan,
Andrea S. Vincent,
George L. Dale
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.581447
Subject(s) - medicine , intracerebral hemorrhage , bleed , platelet , hemostasis , spontaneous intracerebral hemorrhage , thrombin , anesthesia , mean platelet volume , platelet activation , surgery , subarachnoid hemorrhage
Coated platelets are produced on dual agonist stimulation with collagen and thrombin. These highly procoagulant platelets are critical to normal hemostasis, and an earlier study demonstrated decreased coated platelet production in patients with spontaneous intracerebral hemorrhage. We have expanded this observation to investigate if coated platelet levels correlate with bleed volume in spontaneous intracerebral hemorrhage.
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