Chromosome 9p21 in Ischemic Stroke | Zendy

Christopher D. Anderson | Zendy; Alessandro Biffi | Zendy; Natalia S. Rost | Zendy; Lynelle Cortellini | Zendy; Karen L. Furie | Zendy; Jonathan Rosand | Zendy

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Chromosome 9p21 in Ischemic Stroke

Author(s) -

Christopher D. Anderson,

Alessandro Biffi,

Natalia S. Rost,

Lynelle Cortellini,

Karen L. Furie,

Jonathan Rosand

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.580589

Subject(s) - medicine , population stratification , stroke (engine) , population , cardiology , coronary artery disease , myocardial infarction , linkage disequilibrium , confounding , single nucleotide polymorphism , infarction , genetics , genotype , biology , gene , mechanical engineering , environmental health , engineering

Sequence variants on chromosome 9p21.3 are implicated in coronary artery disease and myocardial infarction, but studies in ischemic stroke have produced inconsistent results. We investigated whether these conflicting findings were due to false-positive studies confounded by population stratification or false-negative studies that failed to account for effects specific to certain stroke subtypes.

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