Watershed Infarcts in Transient Ischemic Attack/Minor Stroke With ≥50% Carotid Stenosis
Author(s) -
Ramez Reda Moustafa,
David IzquierdoGarcia,
P. Simon Jones,
Martin J. Graves,
Tim D. Fryer,
Jonathan H. Gillard,
Elizabeth A. Warburton,
JeanClaude Baron
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.110.580415
Subject(s) - medicine , stenosis , minor stroke , stroke (engine) , cardiology , ischemic stroke , ischemia , mechanical engineering , engineering
Watershed ischemia is a significant cause of stroke in severe carotid disease, but its pathophysiology is unsettled. Although hemodynamic compromise has long been regarded as the main mechanism-particularly with deep watershed infarction-there is some contradictory evidence from clinical and pathological studies for a role of microembolism, thought to result from plaque inflammation. However, no study so far has directly addressed these conflicting scenarios.
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