Weight Approximation in Stroke Before Thrombolysis | Zendy

Lorenz Breuer | Zendy; Tim Nowe | Zendy; Hagen B. Huttner | Zendy; C. Blinzler | Zendy; Rainer Kollmar | Zendy; Peter D. Schellinger | Zendy; Stefan Schwab | Zendy; Martin Köhrmann | Zendy

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Weight Approximation in Stroke Before Thrombolysis

Author(s) -

Lorenz Breuer,

Tim Nowe,

Hagen B. Huttner,

C. Blinzler,

Rainer Kollmar,

Peter D. Schellinger,

Stefan Schwab,

Martin Köhrmann

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.110.578062

Subject(s) - dosing , medicine , thrombolysis , stroke (engine) , body weight , anthropometry , tissue plasminogen activator , emergency department , emergency medicine , surgery , mechanical engineering , myocardial infarction , engineering , psychiatry

Because of the narrow therapeutic range for thrombolysis in stroke, accurate weight-based dosing is essential for efficacy and safety. Stroke patients are frequently incapable to communicate their correct body weight (BW). Thus, dosing is often based on BW estimation, which may lead to dosing errors. The aim of our study was to evaluate availability of BW information, accuracy of estimations, and final dosing of Alteplase (tissue plasminogen activator [tPA]) in a routine clinical setting.

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