Lesion Load of the Corticospinal Tract Predicts Motor Impairment in Chronic Stroke | Zendy

Lin Zhu | Zendy; Robert Lindenberg | Zendy; Michael P. Alexander | Zendy; Gottfried Schlaug | Zendy

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Lesion Load of the Corticospinal Tract Predicts Motor Impairment in Chronic Stroke

Author(s) -

Lin Zhu,

Robert Lindenberg,

Michael P. Alexander,

Gottfried Schlaug

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.577023

Subject(s) - lesion , medicine , corticospinal tract , diffusion mri , stroke (engine) , motor impairment , physical medicine and rehabilitation , hemiparesis , magnetic resonance imaging , radiology , surgery , mechanical engineering , engineering

Previous studies have shown motor impairment after a stroke relates to lesion size and location, but unexplained variability in recovery still exists. In this study, we used lesion-mapping techniques in combination with diffusion tensor imaging to quantitatively test the hypothesis that motor recovery in patients with chronic stroke is inversely related to the proportion of the corticospinal tract (CST) affected by the lesion.

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