Endothelial Activation in Lacunar Stroke Subtypes | Zendy

Iris L.H. Knottnerus | Zendy; José W.P. GoversRiemslag | Zendy; Karly Hamulyák | Zendy; Rob P.W. Rouhl | Zendy; Julie Staals | Zendy; Henri M.H. Spronk | Zendy; René van Oerle | Zendy; E.P.M. van Raak | Zendy; J. Lodder | Zendy; Hugo Ten Cate | Zendy; Robert J. van Oostenbrugge | Zendy

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Endothelial Activation in Lacunar Stroke Subtypes

Author(s) -

Iris L.H. Knottnerus,

José W.P. GoversRiemslag,

Karly Hamulyák,

Rob P.W. Rouhl,

Julie Staals,

Henri M.H. Spronk,

René van Oerle,

E.P.M. van Raak,

J. Lodder,

Hugo Ten Cate,

Robert J. van Oostenbrugge

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.576223

Subject(s) - medicine , asymptomatic , thrombomodulin , von willebrand factor , lacunar stroke , plasminogen activator , tissue plasminogen activator , tissue factor , endothelium , leukoaraiosis , gastroenterology , hyperintensity , stroke (engine) , fibrinolysis , endothelial activation , concomitant , endothelial dysfunction , cardiology , pathology , coagulation , magnetic resonance imaging , platelet , ischemic stroke , thrombin , dementia , disease , ischemia , mechanical engineering , radiology , engineering

Lacunar stroke (LS) can be subtyped according to the absence (isolated lacunar infarct [ILA]) or presence of concomitant white matter lesions (WML) and/or asymptomatic lacunar infarcts. Endothelial activation is thought to play a pivotal role in the subtype with WML and/or asymptomatic lacunar infarcts. The aim of this study was to evaluate whether endothelial activation is associated with WML and/or asymptomatic lacunar infarcts in LS patients. Here, we determined levels of circulating blood markers of endothelial function in LS patients.

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