Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9 | Zendy

Taura L. Barr | Zendy; Lawrence L. Latour | Zendy; KyungYul Lee | Zendy; Timothy J. Schaewe | Zendy; Marie Luby | Zendy; George S. Chang | Zendy; Ziad El-Zammar | Zendy; Shaista Alam | Zendy; John M. Hallenbeck | Zendy; Chelsea S. Kidwell | Zendy; Steven Warach | Zendy

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Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9

Author(s) -

Taura L. Barr,

Lawrence L. Latour,

KyungYul Lee,

Timothy J. Schaewe,

Marie Luby,

George S. Chang,

Ziad El-Zammar,

Shaista Alam,

John M. Hallenbeck,

Chelsea S. Kidwell,

Steven Warach

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.570515

Subject(s) - medicine , odds ratio , blood–brain barrier , confidence interval , cerebrospinal fluid , stroke (engine) , intracerebral hemorrhage , matrix metalloproteinase 9 , matrix metalloproteinase , gastroenterology , pathology , subarachnoid hemorrhage , central nervous system , mechanical engineering , engineering

Matrix metalloproteinases (MMP) may play a role in blood-brain barrier (BBB) disruption after ischemic stroke. We hypothesized that plasma concentrations of MMP-9 are associated with a marker of BBB disruption in patients evaluated for acute stroke.

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