Mismatch-Based Delayed Thrombolysis | Zendy

Nishant K. Mishra | Zendy; Gregory W. Albers | Zendy; Stephen M. Davis | Zendy; Geoffrey A. Donnan | Zendy; Anthony J. Furlan | Zendy; Werner Hacke | Zendy; Kennedy R. Lees | Zendy

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Mismatch-Based Delayed Thrombolysis

Author(s) -

Nishant K. Mishra,

Gregory W. Albers,

Stephen M. Davis,

Geoffrey A. Donnan,

Anthony J. Furlan,

Werner Hacke,

Kennedy R. Lees

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.566869

Subject(s) - medicine , thrombolysis , stroke (engine) , clinical trial , odds ratio , intracerebral hemorrhage , odds , fibrinolytic agent , randomized controlled trial , cardiology , surgery , tissue plasminogen activator , logistic regression , subarachnoid hemorrhage , myocardial infarction , mechanical engineering , engineering

Clinical benefit from thrombolysis is reduced as stroke onset to treatment time increases. The use of "mismatch" imaging to identify patients for delayed treatment has face validity and has been used in case series and clinical trials. We undertook a meta-analysis of relevant trials to examine whether present evidence supports delayed thrombolysis among patients selected according to mismatch criteria.

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