Open AccessBrain-Derived Neurotrophic Factor Stimulates Production of Prostacyclin in Cerebral Arteries
Author(s) -
Anantha Vijay R. Santhanam,
Leslie Smith,
Zvonimir S. Katušić
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.564492
Subject(s) - endocrinology , medicine , prostacyclin , basilar artery , arachidonic acid , cyclic guanosine monophosphate , cerebral arteries , nitric oxide synthase , nitric oxide , biology , enzyme , biochemistry
The role of brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin receptor kinase B, in control of cerebral circulation is poorly understood. The present study was designed to investigate the cerebral vascular effects of BDNF in vivo.
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