Pre–Tissue Plasminogen Activator Blood Pressure Levels and Risk of Symptomatic Intracerebral Hemorrhage | Zendy

Georgios Tsivgoulis | Zendy; James L. Frey | Zendy; Murray Flaster | Zendy; Vijay K. Sharma | Zendy; Annabelle Y. Lao | Zendy; Steven L. Hoover | Zendy; Wei Liu | Zendy; Elefterios Stamboulis | Zendy; Anne W. Alexandrov | Zendy; Marc Malkoff | Zendy; Andrei V. Alexandrov | Zendy

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Pre–Tissue Plasminogen Activator Blood Pressure Levels and Risk of Symptomatic Intracerebral Hemorrhage

Author(s) -

Georgios Tsivgoulis,

James L. Frey,

Murray Flaster,

Vijay K. Sharma,

Annabelle Y. Lao,

Steven L. Hoover,

Wei Liu,

Elefterios Stamboulis,

Anne W. Alexandrov,

Marc Malkoff,

Andrei V. Alexandrov

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.564096

Subject(s) - medicine , blood pressure , contraindication , thrombolysis , tissue plasminogen activator , stroke (engine) , intracerebral hemorrhage , anesthesia , surgery , myocardial infarction , subarachnoid hemorrhage , pathology , mechanical engineering , alternative medicine , engineering

From small pilot studies, uncontrolled pretreatment systolic blood pressure >185 mm Hg and diastolic blood pressure >110 mm Hg in patients with acute ischemic stroke were introduced in the National Institute of Neurological Diseases and Stroke rtPA Stroke Study as a contraindication for thrombolysis. We sought to determine if pretreatment blood pressure protocol violations in patients with acute ischemic stroke receiving intravenous tissue plasminogen activator are related to the subsequent risk of symptomatic intracranial hemorrhage (sICH).

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